MAR002 is an early, promising development: a new take on a proven strategy, with the potential for stronger IGF-1 control and dramatically less frequent dosing. At the same time, it’s important to keep expectations grounded. The drug is still investigational. It is not approved, not yet available outside clinical trials, and a larger patient study is needed to confirm what the early data suggest.
From Lewis Blevins, MD Introduction Growth Hormone is a peptide hormone produced by the anterior pituitary gland. Growth hormone-releasing hormone from the hypothalamus stimulates it’s release while somatostatin from the hypothalamus inhibits GH. Somatostatin is
From Lewis Blevins. MD – Polyuria in the setting of thirst and increased water intake, with a dilute urine, and a high or high normal serum sodium (>141-142 mEq/L) is usually recognizable as DI. Some
From Lewis Blevins, MD – These images show the serial visual fields in a patient with a pituitary tumor. The blackened parts illustrate what the patient CANNOT see as if they were our very
From Lewis Blevins, MD – Empty sella syndrome as a misnomer for the sella is not empty. It is usually filled with spinal fluid. Furthermore, a true syndrome does not exist. An empty sella
From Lewis Blevins, MD – We really shouldn’t call them nonfunctional pituitary adenomas. They are living tissue and thus “functioning.” The term comes from the fact that they are not producing any hormones in excess
From J D Faccinetti – There are several expert sources that have focused research on the prevalence of pituitary tumors. Estimates on these studies varied from as high as 30 percent to as low
From Lewis Blevins, MD – Photo from The Huffington Post – Testosterone use in men has been “associated” with cardiovascular risk. In my opinion, this is because men with cardiovascular disease, who are obviously sick,
From Lewis Blevins. MD I’ve been asked on at least two occasions to comment on oxytocin in patients with hypothalamic and pituitary disorders. Oxytocin is a fascinating hormone made by the hypothalamus. It is stored
From Lewis Blevins, MD – Image from UPMC – The hypothalamus is recognized as the part of the brain that surrounds the third ventricle. It contains the cell bodies of neurons that release hypothalamic hormones
Welcome to Pituitary World News. Our goal is to educate, inform and provide a platform to exchange ideas with those who have an interest in the pituitary gland and its disorders. We are affected patients, their