Some pituitary tumors occur as a result of heritable conditions. Dr. Korbonits and her group have remarkably advanced our understanding of the genetics of inherited pituitary disorders. She has elucidated the genetic cause of acromegaly (AIP mutation) in the Irish Giant!
From the NY Times this is a fascinating article relating the recent discoveries on the genetics of Acromegaly in the legendary Irish Giant. His story is a rather fascinating one of suffering and death followed by a body snatch and then by medical research conducted more than two centuries after his death!
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