We’re thrilled to welcome you back to Crinetics Pharmaceuticals in San Diego for a special conversation with two of our favorite guests – co-founders Dr. Scott Struthers (CEO) and Dr. Steven Betz (Chief Scientific Officer). Since we first met back in 2017 at a conference in New Orleans, we’ve watched Crinetics grow from a 35-person team into a fully integrated pharmaceutical company that’s now bringing real hope to patients through Palsonify™ for acromegaly and a series of promising drugs in the pipeline. It’s been an incredible journey to witness!
In this episode, we sit down to talk about how it all began. Why they decided to go it alone instead of partnering with big pharma (spoiler: it wasn’t always easy!). Those make-or-break moments when the path forward wasn’t clear. What they’re doing to make sure patients can actually access Palsonify™. Exciting developments in their pipeline, including trials for Atumelnant, a new drug for Congenital Adrenal Hyperplasia (CAH) with very promising prospects, and the lessons they’re carrying forward as they continue pushing boundaries in rare disease treatment.
This is a candid, inspiring conversation about perseverance, innovation, and what it really takes to bring life-changing therapies from lab to patient.
If you’d like to listen to some of our past chats with these two engaging scientists please click on the links below.
- This is a fascinating chat with Scott in 2017 when CRN808, now Palsonify™, was entering clinical trials.
- This podcast from January 2020, which we recorded late in 2019, is the first in a series of 6 podcasts on the ins and outs of drug development and will give you a perspective of where Crinetics was 7 years ago.
If you found this conversation and our content valuable, please share it with your friends, family, and healthcare providers. Too many people with pituitary and adrenal diseases wait years for an accurate diagnosis. By raising awareness together, we can help more patients get the care they need sooner.
Click on this link for more information on Crinetics support for patients.
Watch the video of the podcast
© 2026, J D Faccinetti. All rights reserved.